Acetohydroxamic Acid

Pronunciation

 (a SEE toe hye droks am ik AS id)

U.S. Brand Names

 Lithostat

Synonyms

 AHA

Generic Available

 No

Canadian Brand Names

 Lithostat

Use

 Adjunctive therapy in chronic urea-splitting urinary infection

Pregnancy Risk Factor

 X

Lactation

 Excretion in breast milk unknown/not recommended

Ethanol/Nutrition/Herb Interactions

 Ethanol: Avoid ethanol (may increase incidence of rash)

Dosage

 Oral:

Children: Initial: 10 mg/kg/day

Adults: 250 mg 3-4 times/day for a total daily dose of 10-15 mg/kg/day

Dietary Considerations

 Should be taken 1 hour before or 2 hours after meals.

Patient Education

 Take as directed, preferably 1 hour before or 2 hours after meals. Avoid alcohol (rash may occur). You may experience increased anxiety, malaise, or headache; use caution when driving or engaging in hazardous tasks until response is known. Small, frequent meals may reduce incidence of nausea. Report persistent acute headache, nausea, or vomiting. Pregnancy/breast-feeding precautions: Inform prescriber if you are pregnant. Do not get pregnant or have sex unless using appropriate contraception while on this medication. This drug may cause severe fetal defects. Consult prescriber if breast-feeding.

Dental Health: Effects on Dental Treatment

 No significant effects or complications reported

Dental Health: Vasoconstrictor/Local Anesthetic Precautions

 No information available to require special precautions

Mental Health: Effects on Mental Status

 None reported

Mental Health: Effects on Psychiatric Treatment

 None reported

Dosage Forms

 Tablet: 250 mg

International Brand Names

 Lithostat (CA); Uronefrex (BE, ES, LU)

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