OverviewLemon balm (Melissa officinalis), a member of the mint family, is considered a "calming" herb. It was used as far back as the Middle Ages to reduce stress and anxiety, promote sleep, improve appetite, and ease pain and discomfort from indigestion (including gas and bloating as well as colic). Even before the Middle Ages, lemon balm was steeped in wine to lift the spirits, help heal wounds, and treat venomous insect bites and stings. Today, lemon balm is often combined with other calming, soothing herbs, such as valerian, chamomile, and hops, to help promote relaxation. It is also used in creams to treat cold sores (oral herpes).
Plant DescriptionNative to Europe, lemon balm is grown all over the world. It is grown not only in herb gardens or to attract bees, but also in crops for medicine, cosmetics, and furniture polish manufacturing. The plant grows up to 2 feet in height, sometimes higher if not maintained. In the spring and summer, clusters of small, light yellow flowers grow where the leaves meet the stem. The leaves are very deeply wrinkled and range from dark green to yellowish green in color, depending on the soil and climate. If you rub your fingers on these leaves, your fingers will smell tart and sweet, like lemons. The leaves are similar in shape to mint leaves, and come from the same plant family.
Medicinal Uses and IndicationsInsomnia and anxiety Several studies have found that lemon balm combined with other calming herbs (such as valerian, hops, and chamomile) helps reduce anxiety and promote sleep. Few studies have examined lemon balm by itself, except for topical use. For example, in one study of people with minor sleep problems, those who took an herbal combination of valerian and lemon balm reported sleeping much better than those who took placebo. But it's not clear from this and other studies whether it is lemon balm or valerian (or the combination) that were responsible for the result. The same is true of several studies for anxiety, which used a combination of herbs to reduce symptoms. In another double-blind, placebo-controlled study, 18 healthy volunteers received two separate single doses of a standardized lemon balm extract (300 mg and 600 mg) or placebo for 7 days. The 600 mg dose of lemon balm increased mood and significantly increased calmness and alertness. Herpes Some studies suggest that topical ointments containing lemon balm may help heal cold sores caused by the herpes simplex virus (HSV). In one study of 116 people with HSV, those who applied lemon balm cream to their lip sores experienced significant improvement in redness and swelling after only 2 days. Other symptoms, such as pain and scabbing, did not improve. Both the patients and their doctors reported that the lemon balm ointment was highly effective. Several animal studies also support the value of topical lemon balm for herpes lesions. Other uses Some evidence suggests that lemon balm, in combination with other herbs, may help treat indigestion. And a few studies have found that lemon balm may help improve cognitive function and decrease agitation in people with Alzheimer's disease.
What's It Made Of?Lemon balm supplements are made from the leaves of the plant. Essential oils made from lemon balm leaves contain plant chemicals called terpenes, which play at least some role in the herb's relaxing and antiviral effects. Lemon balm also contains substances called tannins, which are thought to cause many of the herb's antiviral effects. Lemon balm also contains eugenol, which calms muscle spasms, numbs tissues, and kills bacteria.
Available FormsLemon balm is available as a dried leaf that can be bought in bulk. It is also sold as tea, and in capsules, extracts, tinctures, and oil. Some creams used in Europe, which contain high levels of lemon balm, are not available in the United States. On the other hand, teas can be applied to the skin with cotton balls. Lemon balm is also available in homeopathic remedies and as aromatherapy (essential oil).
How to Take ItPediatric Lemon balm may be used topically in children to treat cold sores. The dosage would be the same as the recommendations for adults. For internal use, adjust the recommended adult dose to account for the child's weight. Most herbal dosages for adults are calculated on the basis of a 150 lb (70 kg) adult. Therefore, if the child weighs 50 lb (20 - 25 kg), the appropriate dose of lemon balm would be 1/3 of the adult dosage. Adult For difficulty sleeping, or to reduce indigestion, flatulence, or bloating:
For cold sores or herpes sores, steep 2 - 4 teaspoonfuls of crushed leaf in 1 cup boiling water for 10 - 15 minutes. Cool. Apply tea with cotton balls to the sores throughout the day.
PrecautionsThe use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, contain components that can trigger side effects and interact with other herbs, supplements, or medications. For these reasons, herbs should be taken with care, under the supervision of a health care provider qualified in the field of botanical medicine. Lemon balm is generally regarded as safe. Pregnant and breastfeeding women should not take lemon balm.
Possible InteractionsLemon balm is generally regarded as safe. However, it may potentially interact with the following medications: Sedatives, thyroid medications -- Although there is no scientific evidence of this, lemon balm may interact with sedatives and thyroid medications. If you are taking sedatives (for insomnia or anxiety) or medications to regulate your thyroid, ask your doctor before taking lemon balm.
Supporting ResearchAwad R, Levac D, Cybulska P, Merali Z, Trudeau VL, Arnason JT. Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system. Can J Physiol Pharmacol. 2007 Sep;85(9):933-42. Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry. 2002;63(7):553-8. Berdonces JL. Attention deficit and infantile hyperactivity. [Spanish]. Rev Enferm. 2001;24(1):11-14. Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:230-232. de Sousa AC, Alviano DS, Blank AF, Alves PB, Alviano CS, Gattass CR. Melissa officinalis L. essential oil: antitumoral and antioxidant activities. J Pharm Pharmacol. 2004;56(5):677-81. Dos Santos-Neto LL, de Vilhena Toledo MA, Medeiros-Souza P, de Souza GA. The use of herbal medicine in Alzheimer's disease-a systematic review. Evid Based Complement Alternat Med. 2006 Dec;3(4):441-5. Ernst E. The Desktop Guide to Complementary and Alternative Medicine: An Evidence-Based Approach. Mosby, Edinburgh; 2001:169. Gaby AR. Natural remedies for Herpes simplex. Altern Med Rev. 2006;11(2):93-101. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines, 4th ed. Montvalie, NJ: Thomson Healthcare; 2007:514-515. Kennedy DO, Little W, Haskell CF, Scholey AB. Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. Phytother Res. 2006;20(2):96-102. Kennedy DO, Scholey AB, Tildesley NT, Perry EK, Wesnes KA. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004 Jul-Aug;66(4):607-13. Kennedy DO, Wake G, Savelev S, et al., Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacology. 2003;28(10):1871-81. LaValle JB, Krinsky DL, Hawkins EB, et al. Natural Therapeutics Pocket Guide. Hudson, OH:LexiComp; 2000: 469. Madisch A, Melderis H, Mayr G, Sassin I, Hotz J. A plant extract and its modified preparation in functional dyspepsia. Results of a double-blind placebo controlled comparative study. [German]. Z Gastroenterol. 2001;39(7):511-517. Mantle D, Pickering AT, Perry AK. Medicinal plant extracts for the treatment of dementia: a review of their pharmacology, efficacy and tolerability. CNS Drugs. 2000;13:201-213. Mazzanti G, Battinelli L, Pompeo C, Serrilli AM, Rossi R, Sauzullo I, et al. Inhibitory activity of Melissa officinalis L. extract on Herpes simplex virus type 2 replication. Nat Prod Res. 2008;22(16):1433-40. Muller SF, Klement S. A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine. 2006;13(6):383-7. Nolkemper S, Reichling J, Stintzing FC, Carle R, Schnitzler P. Antiviral Effect of Aqueous Extracts from Species of the Lamiaceae Family against Herpes simplex Virus Type 1 and Type 2 in vitro. Planta Med. 200672(15):1378-82. Patora J, Klimek B. Flavonoids from lemon balm (Melissa officinalis L., Lamiaceae). Acta Pol Pharm. 2002;59(2):139-43. Rotblatt M, Ziment I. Evidence-Based Herbal Medicine. Philadelphia, PA: Hanley & Belfus, Inc; 2002:249-251. Triantaphyllou K, Blekas G, Boskou D. Antioxidative properties of water extracts obtained from herbs of the species Lamiaceae. Int J Food Sci Nutr. 2001;52(4):313-317.
Review Date:
3/22/2009 Reviewed By: Steven D. Ehrlich, NMD, private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-
A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited. |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Disclaimer: The information contained in this website, and its associated websites, is provided as a benefit to the local community, and the Internet community in general; it does not constitute medical advice. We try to provide quality information, but we make no claims, promises or guarantees about the accuracy, completeness, or adequacy of the information contained in or linked to this website and its associated sites. As medical advice must be tailored to the specific circumstances of each patient and healthcare is constantly changing, nothing provided herein should be used as a substitute for the advice of a competent physician. Furthermore, in providing this service, Adventist HealthCare does not condone or support all of the content covered in this site. As an Adventist health care organization, Adventist HealthCare acts in accordance with the ethical and religious directives for Adventist health care services.