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Possible Interactions with: Echinacea

Also listed as: Echinacea; Echinacea angustifolia; Echinacea pallida; Echinacea purpurea; Purple Coneflower
Table of Contents > Herb Interactions > Possible Interactions with: Echinacea

Interactions

If you are taking any of the following medications, you should not use echinacea without first talking to your healthcare provider:

Econazole echinacea may be useful in combination with econazole, an antifungal agent used to treat yeast infections (such as athlete's foot). When echinacea is used together with econazole, recurrence rates of these infections may be reduced.

Immunosuppressants Immunosuppressants refers to a group of medications that are used for two main purposes -- treat cancer and suppress the immune system following organ transplant so that the new organ is not rejected. Because echinacea can enhance immune function, people should not use the herb with immunosuppressive medications, especially when taken for organ transplant.

In terms of cancer treatment, a couple of test tube studies imply that echinacea may be useful when used in combination with cyclophosphamide, one medication in this class. Using echinacea with this or other chemotherapy agents that act as immunosuppressants, may allow the cancer-fighting medicines to kill the tumors while still protecting the immune system. If this theory proves to be correct then echinacea could possibly prevent many of the side effects of chemotherapy.

Drug Interactions

Review Date: 9/22/2005
Reviewed By: A.D.A.M. editorial. Previously reviewed by Constance Grauds, RPh (April 1999), President, Association of Natural Medicine Pharmacists, San Rafael, CA; Jacqueline A. Hart, MD, Department of Internal Medicine, Newton-Wellesley Hospital, Harvard University and Senior Medical Editor Integrative Medicine, Boston, MA; Gary Kracoff, RPh (Pediatric Dosing section February 2001), Johnson Drugs, Natick, MA; Enrico Liva, ND, RPh, Vital Nutrients, Middletown, CT; Steven Ottariono, RPh (Pediatric Dosing section February 2001), Veteran's Administrative Hospital, Londonderry, NH; David Winston, Herbalist (April 1999), Herbalist and Alchemist, Inc., Washington, NJ; Tom Wolfe, P.AHG (April 1999), Smile Herb Shop, College Park, MD. All interaction sections have also been reviewed by a team of experts including Joseph Lamb, MD (July 2000), The Integrative Medicine Works, Alexandria, VA;Brian T Sanderoff, PD, BS in Pharmacy (March 2000), Clinical Assistant Professor, University of Maryland School of Pharmacy; President, Your Prescription for Health, Owings Mills, MD; R. Lynn Shumake, PD (March 2000), Director, Alternative Medicine Apothecary, Blue Mountain Apothecary & Healing Arts, University of Maryland Medical Center, Glenwood, MD; Ira Zunin, MD, MPH, MBA (July 2000), President and Chairman, Hawaii State Consortium for Integrative Medicine, Honolulu, HI.
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