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Gout

Table of Contents > Conditions > Gout     Print

Signs and Symptoms
What Causes It?
What to Expect at Your Provider's Office
Treatment Options
 
Following Up
Special Considerations
Supporting Research

Gout is a type of arthritis that occurs when too much uric acid builds up in the body, causing crystals to form in joints, and joints to become inflamed. It can be hereditary or the result of another condition. Gout usually affects men over 40 with a family history of gout, but it can occur at any time and also affects women, especially after menopause. Excessive intake of food and alcohol, surgery, infection, physical or emotional stress, or the use of certain drugs can lead to the development of gout symptoms.

Signs and Symptoms

  • Extreme pain in a single joint, usually the base of the big toe; it can also affect other joints (such as the feet, fingers, wrists, elbows, knees, or ankles).
  • Joint is shiny red-purple, swollen, hot, and stiff.
  • Fever as high as 39°C (102.2°F) with or without chills.
  • Symptoms can develop very quickly, with the first episode often occurring at night, then go away after 5 - 10 days only to come back later.
  • In later attacks, you may see lumps (called tophi) just under the skin in the outer ear, hands, feet, elbow, or knee.

What Causes It?

The body produces too much uric acid, doesn't excrete enough uric acid, or both, so that the acid accumulates in tissues in the form of needle-like crystals that cause pain. Gout generally occurs because of a predisposition to the condition, but it can result from blood disorders or cancers, such as leukemia, or the use of certain drugs. Risk factors include:

  • Family history of gout
  • High levels of triglycerides
  • Drinking too much alcohol
  • Eating foods rich in purines, such as meat, shellfish, and sweetbreads. Uric acid is formed when purines break down.

What to Expect at Your Provider's Office

Your health care provider will examine the affected joint, evaluate your pain, and may ask if there is any history of gout in your family. Your health care provider may take a sample of fluid from the affected joint, draw blood for a blood test, or take x-rays to rule out other possibilities.

Treatment Options

Your health care provider may give you ibuprofen or another nonsteroidal anti-inflammatory drug (NSAID) to help with the pain and swelling. You must avoid alcohol and foods that trigger your attacks. Besides NSAIDs, you may recieve other drugs. Colchicine can help treat an acute attack and prevent future attacks but has serious side effects. Probenecid (Benemid), allopurinol (Zyloprim), and sulfinpyrazone (Anturane) also help prevent future attacks. These drugs help control gout but do not cure it.

Complementary and Alternative Therapies

A combination of therapies can be very effective at decreasing both the length and frequency of attacks.

Nutrition and Supplements

These nutritional tips may help reduce symptoms:

  • Eliminate potential food allergens, including dairy, wheat (gluten), corn, preservatives, and food additives. Your healthcare provider may test for food sensitivities.
  • Eat antioxidant foods, including fruits (such as blueberries, cherries, and tomatoes), and vegetables (such as squash and bell peppers). One half pound of cherries per day (fresh or frozen) for 2 weeks lowers uric acid and prevents attacks. Cherry juice (8 - 16 oz. per day) is also helpful.
  • Eat more high fiber foods, including beans, oats, root vegetables (such as potatoes and yams), and psyllium seed.
  • Avoid refined foods, such as white breads, pastas, and sugar.
  • Eat fewer red meats and more lean meats, cold-water fish, tofu (soy, if no allergy) or beans for protein.
  • Cut down on oxalate-containing foods, such as spinach, rhubarb, beets, nuts, chocolate, black tea, wheat bran, strawberries, and beans.
  • Include foods rich in magnesium and low in calcium, such as barley, bran, corn, rye, oats, soy, brown rice, avocado, banana, and potato.
  • Restrict purines in your diet. Foods with a high purine content include beef, goose, organ meats, sweetbreads, mussels, anchovies, herring, mackerel, and yeast. Foods with a moderate amount of purines include meats, poultry, fish, and shellfish not listed above. Spinach, asparagus, beans, lentils, mushrooms, and dried peas also contain moderate amounts of purines.
  • Use healthy cooking oils, such as olive oil or vegetable oil.
  • Reduce or eliminate trans-fatty acids, found in commercially baked goods such as cookies, crackers, cakes, French fries, onion rings, donuts, processed foods, and margarine.
  • Avoid coffee and other stimulants, alcohol, and tobacco.
  • Drink six to eight glasses of filtered water daily to help flush uric acid from the body. Dehydration often triggers a gout attack.
  • Exercise at least 30 minutes daily, 5 days a week.

You may address nutritional deficiencies with the following supplements:

  • A multivitamin daily, containing the antioxidant vitamins A, C, E, the B-complex vitamins, and trace minerals such as magnesium, calcium, zinc and selenium.
  • Omega-3 fatty acids, such as fish oil, 1- 2 capsules or 1 tablespoons of oil daily, to help decrease inflammation and help in general health. Cold-water fish, such as salmon or halibut, are good sources. Talk to your health care provider before taking omega-3 supplements if you are taking blood thinning medications, such as aspirin or warfarin (Coumadin).
  • IP-6 (inositol hexophosphonate), 1 - 8 grams daily on an empty stomach, for kidney health. Check with your alternative healthc are provider for proper dosing.
  • N-acetyl cysteine, 200 mg daily, for antioxidant effects.
  • Vitamin C, 500 - 1,000 mg daily, as an antioxidant.
  • Acidophilus (Lactobacillus acidophilus), 5 - 10 billion CFUs (colony forming units), when needed for maintenance of gastrointestinal and immune health. Some acidophilus products may need refrigeration. Check the labels carefully.
  • Methylsulfonylmethane (MSM), 3,000 mg twice a day, to help decrease inflammation.
  • Avoid taking extra niacin and vitamin A. Both may play a role in some attacks of gout.

Herbs

Herbs are generally a safe way to strengthen and tone the body's systems. As with any therapy, you should work with your health care provider to get your problem diagnosed before starting any treatment. You may use herbs as dried extracts (capsules, powders, teas), glycerites (glycerine extracts), or tinctures (alcohol extracts). Unless otherwise indicated, you should make teas with 1 tsp. herb per cup of hot water. Steep covered 5 - 10 minutes for leaf or flowers, and 10 - 20 minutes for roots. Drink two to four cups per day. You may use tinctures alone or in combination as noted.

  • Cranberry (Vaccinium macrocarpon) standardized extract, 300 - 400 mg daily, for kidney health. You may also take 8-16 ounces of unsweetened cranberry juice daily.
  • Green tea (Camelia sinensis) standardized extract, 250 - 500 mg daily, for antioxidant and immune effects. Use caffeine-free products. You may also prepare teas from the leaf of this herb.
  • Devil's claw (Harpagophytum procumbens), standardized extract, 750 mg three times daily, for pain and inflammation.
  • Cat's claw (Uncaria tomentosa) standardized extract, 20 mg three times a day, for inflammation, immune, and antibacterial/antifungal activity.
  • Bromelain (Ananus comosus) standardized extract, 40 mg three times daily, for pain and inflammation.
  • Turmeric (Curcuma longa ) standardized extract, 300 mg three times a day, for inflammation.

Homeopathy

Although few studies have examined the effectiveness of specific homeopathic therapies, professional homeopaths may consider the following remedies for the treatment of gastritis symptoms (such as nausea and vomiting) based on their knowledge and experience. Before prescribing a remedy, homeopaths take into account your constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for you individually.

Some of the most common remedies used for gout are listed below. A common dose is three to five pellets of a 12X to 30C remedy every 1 - 4 hours until your symptoms improve.

  • Aconite for sudden onset of burning pain, anxiety, restlessness, and attacks that come after a shock or injury. Also take if your joints are swollen and painful.
  • Belladonna for intense pain that may be throbbing, if pain is made worse by any motion and better by pressure, or if the joint is very hot.
  • Berberis vulgaris for spasms of pain in joints or twinges made worse by walking. There may be back pain and a tendency to develop kidney stones.
  • Bryonia for pain made much worse by any kind of motion, or if pain is better with pressure and with heat.
  • Colchicum for pains made worse by motion and changes of weather, especially if there is any nausea associated with the attacks.
  • Ledum when joints become mottled, purple, and swollen, or if the pain is much better with cold applications and is worse when overheated.
  • Rhus toxicodendron for stiff, swollen joints that are hot and painful, or if the pain is worse with cold applications and better with heat.

Physical Medicine

  • Hot and cold compresses -- Alternating hot compress for 3 minutes with a cold one for 30 seconds provides pain relief and increases circulation.
  • Nettle tea compress, applied externally. Use 1 - 2 tsp. per cup of hot water.

Following Up

If you have had several attacks and the joint is damaged, your health care provider may refer you to an orthopedic specialist.

Special Considerations

People who have had gout have an increased risk of developing kidney stones, high blood pressure, kidney disease, diabetes, high levels of triglycerides, and atherosclerosis.

Supporting Research

Choi HK, Curhan G. Soft drinks, fructose consumption, and the risk of gout in men: prospective cohort study. BMJ. 2008; [Epub ahead of print].

Choi HK. Diet, alcohol, and gout: how do we advise patients given recent developments? Curr RheumatolRep. 2005;7(3):220-6.

Eggebeen AT. Gout: an update. Am Fam Physician. 2007;76(6):801-8. Review.

Falasca GF. Metabolic diseases: gout. Clin Dermatol. 2006;24(6):498-508.

Gagnier JJ, Chrubasik S, Manheimer E. Harpgophytum procumbens for osteoarthritis and low back pain: a systematic review. BMC Complement Altern Med. 2004 Sep 15;4:13.

Lee SJ, Terkeltaub RA, Kavanaugh A. Recent developments in diet and gout. Curr Opin Rheumatol. 2006;18(2):193-8.

Li EK. Gout: a review of its aetiology and treatment. Hong Kong Med J. 2004;10(4):261-70.

Pascual E, Sivera F. Therapeutic advances in gout. Curr Opin Rheumatol. 2007;19(2):122-7.

Saag KG, Choi H. Epidemiology, risk factors, and lifestyle modifications for gout. ArthritisRes Ther. 2006;8 Suppl 1:S2.

Schumacher HR Jr, Chen LX. Newer therapeutic approaches: gout. Rheum Dis Clin North Am. 2006;32(1):235-44, xii. Review.

Wegener T, Lupke NP. Treatment of patients with arthrosis of hip or knee with an aqueous extract of devil's claw (Harpagophytum procumbens DC.). Phytother Res 2003;17(10):1165-1172.

Review Date: 2/12/2008
Reviewed By: Steven D. Ehrlich, NMD, private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network. Also reviewed by Ernest B. Hawkins, MS, BSPharm, RPh, Health Education Resources.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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