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Anti-inflammatory medications - 5-Aminosalicylic acid derivatives

Table of Contents > Depletions > Anti-inflammatory medications - 5-Aminosalicylic acid derivatives     Print

Medications
Depletions
Editorial Note
Supporting Research
 

Medications

Depletions

Vitamin B9 (Folic Acid)

Low levels of folic acid have been linked to anemia, heart disease, and birth defects.

Editorial Note

The selected depletions information presented here identifies some of the nutrients that may be depleted by certain medications. The signs and symptoms associated with nutrient deficiency may also indicate conditions other than nutrient deficiency. If you are experiencing any of the signs or symptoms mentioned, it does not necessarily mean that you are nutrient deficient. Nutrient depletion depends upon a number of factors, including your medical history, diet, and lifestyle as well as the length of time you have been taking the medication. Please consult your healthcare provider; he or she can best assess and address your individual healthcare needs, and determine if you are at risk for nutrient depletions from these medications as well as others not listed here.

Supporting Research

Ames BN. Micronutrient deficiencies: A major cause of DNA damage. Ann NY Acad Sci. 2000;889:87-106.

Jansen G, van der Heijden J, Oerlemans R, et al. Sulfasalazine is a potent inhibitor of the reduced folate carrier: implications for combination therapies with methotrexate in rheumatoid arthritis.Arthritis Rheum. 2004 Jul;50(7):2130-9.

Pelton R, LaValle J, Hawkins EB, et al. Drug Induced Nutrient Depletion Handb ook. Hudson, OH:LexiComp, Inc.;2001:424-425.

Reynolds E. Vitamin B12, folic acid, and the nervous system. Lancet Neurol. 2006;5(11):949-60.

Schnyder G, Roffi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial. JAMA. 2002;288(8):973-9.

Selhub J. et al. Inhibition of folate enzymes by sulfasalazine. J. Clin. Invest. 61:221-224, 1978.

Review Date: 12/24/2007
Reviewed By: All depletions monographs have been reviewed by a team of experts including Ernest B. Hawkins, MS, BSPharm, RPh, Health Education Resources; Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
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