Clinical Trial Details

USOR 18232

A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Breast and Gynecologic Malignancies


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Full Trial Details:

Condition: Breast Cancer
Study Type: Interventional
Phase: II
Study Start Date: 02/06/2019
Study Completion Date: 07/2022

This is a Phase 1/1b, open-label, dose-escalation, and dose-expansion study to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, and clinical activity of AB928 in combination with pegylated liposomal doxorubicin (PLD) with or without IPI-549, or AB928 in combination with nanoparticle albumin-bound-paclitaxel (NP) in participants with advanced metastatic triple-negative breast cancer or ovarian cancer.


NCT Number
Principal Investigator(s)
John Wallmark, MD
Arcus Biosciences, Inc.
Participant Eligibility
  • Age: 18 - No Maximum
  • Gender: Male, Female


  • Shady Grove Adventist Aquilino Cancer Center
    9905 Medical Center Drive
    Rockville, MD 20850
    Main: 240-826-6297

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