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Randomised, open label, multi-centre study assessing the efficacy and safety of MEDI4736 versus Standard of Care in NSCLC patients with PD-L1 positive tumours.
Study compares once-weekly carfilzomib dosing in combination with dexamethasone to twice-weekly carfilzomib dosing in combination with dexamethasone.
Study evaluates the safety and tolerability of BAX69 in combination with 5-fluorouracil (5-FU)/leucovorin (LV) or panitumumab to determine the recommended phase II dose (RP2D) of each combination.
Study to assess the systemic exposure, effiacy, and safety of 450 mg ceritinib taken with a low-fat meal and 600 mg ceritinib taken with a low-fat meal.
Trial to improve the quality of care to people with heart failure, and to help them gain the greatest benefit from the treatments and health advice they receive
Trial to determine the best way to prevent strokes in people who have a high amount of blockage of their carotid artery but no stroke symptoms related to that blockage.
Study of how doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel work in treating patients with triple negative breast cancer.
Study to evaluate PFS endpoint for acalabrutinib vs ibrutinib in previously treated chronic lymphocytic leukemia.
Study to determine if the addition of radium-223 dichloride to standard treatment is able to prolong life and to delay events specific for prostate cancer.
Study to compare the efficacy of andecaliximab (formerly GS-5745) versus placebo as measured by overall survival.
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