mycophenolic acid

Pronunciation: MYE koe phe NOLE ik AS id

Brand: Myfortic


slide 1 of 6, Myfortic,

180 mg, round, green, imprinted with C

Image of Myfortic
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slide 2 of 6, Myfortic,

360 mg, oval, orange, imprinted with CT

Image of Myfortic
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Mycophenolic Acid

slide 3 of 6, Mycophenolic Acid,

360 mg, oval, pink, imprinted with APO, MYC 360

Image of Mycophenolic Acid
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Mycophenolic Acid

slide 4 of 6, Mycophenolic Acid,

360 mg, oval, pink, imprinted with APO, MYC 360

Image of Mycophenolic Acid
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Mycophenolic Acid

slide 5 of 6, Mycophenolic Acid,

180 mg, round, green, imprinted with M3

Image of Mycophenolic Acid
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Mycophenolic Acid

slide 6 of 6, Mycophenolic Acid,

360 mg, oblong, peach, imprinted with M2

Image of Mycophenolic Acid
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What is the most important information I should know about mycophenolic acid?

This medicine can cause a miscarriage or birth defects when used during pregnancy. Both men and women should use effective birth control to prevent pregnancy during and shortly after treatment with mycophenolic acid.

Using mycophenolic acid may increase your risk of cancer, serious infections, or kidney transplant failure.

Call your doctor right away if you have symptoms such as: fever, swollen glands, weight loss, vomiting or diarrhea, painful urination, a new skin lesion, any change in your mental state, weakness on one side of your body, or pain near your transplanted kidney.

What is mycophenolic acid?

Mycophenolic acid is used with other medicines to prevent organ rejection after a kidney transplant. This medicine is for use in adults and children at least 5 years old.

Mycophenolic acid may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mycophenolic acid?

You should not use this medicine if you are allergic to mycophenolic acid, mycophenolate mofetil, or mycophenolate sodium.

Talk with your doctor about the risks and benefits of mycophenolic acid. This medicine can affect your immune system, which may increase your risk of cancer, serious or fatal infections, or kidney transplant failure.

Tell your doctor if you have ever had:

  • a stomach ulcer or problems with digestion;
  • hepatitis B or C or other a viral infection (may become active or get worse while you are using mycophenolic acid); or
  • a rare inherited enzyme deficiency such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome.

This medicine can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. You will need to have a negative pregnancy test before and during treatment with this medicine. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using mycophenolic acid, and for at least 6 weeks after your last dose.

Sexually active men and their partners should use effective contraception during treatment and for at least 90 days after the last dose.

Mycophenolic acid can make birth control pills less effective. Ask your doctor about using an additional barrier form of birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy.

You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy.

This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. Follow these directions carefully. Ask your doctor if you have any questions.

If a pregnancy occurs during treatment, do not stop taking mycophenolic acid. Call your doctor for instructions. Also call the Mycophenolate Pregnancy Registry (1-800-617-8191).

Mycophenolic acid is sometimes given to pregnant women. Your doctor will decide whether you should use this medicine if you are unable to use other needed transplant medications.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How should I take mycophenolic acid?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal.

Swallow the tablet whole and do not crush, chew, or break it.

Mycophenolic acid (Myfortic) and mycophenolate mofetil (CellCept) are not absorbed equally in the body. Avoid medication errors by using only the brand, form, and strength of this medicine that your doctor has prescribed.

You will need frequent medical tests.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking mycophenolic acid?

Avoid taking an antacid together with mycophenolic acid.

Mycophenolic acid can make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Do not receive a "live" vaccine while using mycophenolic acid. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

You must not donate blood or sperm while using this medicine, and for at least 6 weeks (for blood) or 90 days (for sperm) after your last dose.

What are the possible side effects of mycophenolic acid?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mycophenolic acid may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.

Mycophenolic acid affects your immune system and may increase your risk of cancer or serious infection. Call your doctor right away if you have:

  • fever of 100.5 degrees F or higher, swollen glands, painful mouth sores, cold or flu symptoms, headache, ear pain;
  • stomach pain, vomiting, diarrhea, weight loss;
  • weakness on one side of your body, loss of muscle control;
  • confusion, thinking problems, loss of interest in things that normally interest you;
  • pain or burning when you urinate;
  • dark urine, jaundice (yellowing of the skin or eyes);
  • pain or tenderness around the transplanted kidney;
  • tingly or painful blistering rash on one side of your body;
  • swelling, warmth, redness, or oozing around a skin wound; or
  • a new skin lesion, or a mole that has changed in size or color.

Also call your doctor at once if you have:

  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
  • low blood cell counts --fever, chills, tiredness, flu-like symptoms, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects may include:

  • upset stomach, nausea, vomiting;
  • diarrhea, constipation;
  • low blood cell counts, infections;
  • sleep problems (insomnia);
  • painful urination; or
  • pain after surgery.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mycophenolic acid?

Tell your doctor about all your other medicines, especially:

  • azathioprine;
  • cholestyramine; or
  • antiviral medicine --acyclovir, ganciclovir.

This list is not complete. Other drugs may affect mycophenolic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about mycophenolic acid.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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