amlodipine, hydrochlorothiazide, and olmesartan

amlodipine, hydrochlorothiazide, and olmesartan

Pronunciation: am LOE di peen, HYE droe KLOR oh THYE a zide, and OL me SAR tan

Brand: Tribenzor

Tribenzor

slide 1 of 9, Tribenzor,

5 mg-12.5 mg-20 mg, round, orange, imprinted with C51

Image of Tribenzor
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Tribenzor

slide 2 of 9, Tribenzor,

5 mg-12.5 mg-40 mg, round, yellow, imprinted with C53

Image of Tribenzor
slide 2 of 9
    

Tribenzor

slide 3 of 9, Tribenzor,

5 mg-25 mg-40 mg, oval, yellow, imprinted with C54

Image of Tribenzor
slide 3 of 9
    

Tribenzor

slide 4 of 9, Tribenzor,

10 mg-12.5 mg-40 mg, round, red, imprinted with C55

Image of Tribenzor
slide 4 of 9
    

Tribenzor

slide 5 of 9, Tribenzor,

10 mg-25 mg-40 mg, oval, red, imprinted with C57

Image of Tribenzor
slide 5 of 9
    

Amlodipine/HCTZ/Olmesartan Medoxomil

slide 6 of 9, Amlodipine/HCTZ/Olmesartan Medoxomil,

10 mg-25 mg-40 mg, oval, red, imprinted with 1382

Image of Amlodipine/HCTZ/Olmesartan Medoxomil
slide 6 of 9
    

Amlodipine/HCTZ/Olmesartan Medoxomil

slide 7 of 9, Amlodipine/HCTZ/Olmesartan Medoxomil,

5 mg-25 mg-40 mg, oval, yellow, imprinted with 1385

Image of Amlodipine/HCTZ/Olmesartan Medoxomil
slide 7 of 9
    

Amlodipine/HCTZ/Olmesartan Medoxomil

slide 8 of 9, Amlodipine/HCTZ/Olmesartan Medoxomil,

5 mg-12.5 mg-40 mg, round, yellow, imprinted with 1386

Image of Amlodipine/HCTZ/Olmesartan Medoxomil
slide 8 of 9
    

Amlodipine/HCTZ/Olmesartan Medoxomil

slide 9 of 9, Amlodipine/HCTZ/Olmesartan Medoxomil,

5 mg-12.5 mg-20 mg, round, orange, imprinted with 26

Image of Amlodipine/HCTZ/Olmesartan Medoxomil
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What is the most important information I should know about this medicine?

You should not take this medicine if you are allergic to sulfa drugs, or if you are unable to urinate.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use amlodipine, hydrochlorothiazide, and olmesartan together with any medication that contains aliskiren (a blood pressure medicine).

What is amlodipine, hydrochlorothiazide, and olmesartan

Amlodipine is a calcium channel blocker. Hydrochlorothiazide is a thiazide diuretic (water pill). Olmesartan is an angiotensin II receptor blocker (sometimes called an ARB).

Amlodipine, hydrochlorothiazide, and olmesartan is a combination medicine used to treat high blood pressure (hypertension).

This medicine is usually given after other blood pressure medication did not work.

Amlodipine, hydrochlorothiazide, and olmesartan may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking this medicine?

You should not use this medicine if you are allergic to amlodipine, hydrochlorothiazide, or olmesartan, or:

  • if you are allergic to any sulfa drug; or
  • if you are unable to urinate.

If you have diabetes, do not use amlodipine, hydrochlorothiazide, and olmesartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking this medicine with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

  • kidney disease;
  • liver disease;
  • heart disease;
  • an electrolyte imbalance (such as high levels of calcium, or low levels of potassium or magnesium in your blood);
  • low blood pressure;
  • glaucoma;
  • lupus;
  • gout;
  • diabetes; or
  • a penicillin allergy.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

How should I take this medicine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take this medicine with or without food.

Your chest pain may become worse when you first start taking this medicine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

You can easily become dehydrated while taking this medicine Drink plenty of water each day.

Your blood pressure will need to be checked often.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea.

If you need surgery or medical tests, tell the surgeon ahead of time that you are using this medicine.

It may take up to 2 weeks before your blood pressure improves. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking this medicine?

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Drinking alcohol with this medicine can cause side effects.

Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

What are the possible side effects of this medicine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening chest pain;
  • a light-headed feeling, like you might pass out;
  • an unusual skin rash;
  • pain or burning when you urinate;
  • severe or ongoing diarrhea with weight loss;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • kidney problems --little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • signs of an electrolyte imbalance --increased thirst or urination, confusion, vomiting, constipation, muscle pain or weakness, leg cramps, lack of energy, irregular heartbeats, numbness or tingling, loss of movement.

Common side effects may include:

  • dizziness;
  • headache, tired feeling;
  • swelling in your hands or feet;
  • nausea, diarrhea;
  • runny or stuffy nose, sore throat;
  • muscle spasms;
  • swollen joints; or
  • painful urination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect this medicine?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can affect amlodipine, hydrochlorothiazide, and olmesartan, especially:

  • another a diuretic or "water pill";
  • any other blood pressure medicines;
  • insulin or oral diabetes medicine;
  • steroid medicine;
  • vitamin or mineral supplements that contain potassium;
  • a sedative or opioid medicine;
  • cholesterol-lowering medicine;
  • an antibiotic, antifungal, or antiviral medicine; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and others.

This list is not complete and many other drugs may affect amlodipine, hydrochlorothiazide, and olmesartan. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about amlodipine, hydrochlorothiazide, and olmesartan.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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