Gotu Kola

Gotu Kola

Uses

Botanical names:
Centella asiatica

Parts Used & Where Grown

This plant grows in a widespread distribution in tropical, swampy areas, including parts of India, Pakistan, Sri Lanka, Madagascar, and South Africa. It also grows in Eastern Europe. The roots and leaves are used medicinally.

What Are Star Ratings?

This supplement has been used in connection with the following health conditions:

Used for Why
2 Stars
Chronic Venous Insufficiency
60 to 120 mg daily of a standardized herbal extract
Gotu kola extracts have been found to be successful in treating CVI in preliminary trials.

extracts, standardized to triterpenoid content, have been found successful in small preliminary trials to treat CVI. The amount of extract used in these trials ranged from 60 to 120 mg per day.
2 Stars
Skin Ulcers
Apply an ointment or powder containing 1 to 2% herbal extract daily
Gotu kola extracts may be used topically to help speed wound healing.

 (Centella asiatica) extracts are sometimes used topically to help speed wound healing. Test tube studies have found that extracts of gotu kola high in the active triterpene constituents asiaticosides, madecassoides, asiatic acids, and madecassic acids increase collagen synthesis. An animal study found that topical application of asiaticoside isolated from gotu kola, used in a 0.2% solution, improved healing in nonulcer skin wounds. An overview of three small human clinical trials suggests that topical use of an ointment or powder containing a gotu kola extract high in the active triterpene compounds may speed wound healing in people with slow-healing skin ulcers. These studies used either a topical ointment with a 1% extract concentration or a powder with a 2% extract concentration. People in these studies were typically treated with intramuscular injections of either isolated asiaticosides or the mixed triterpenes three times per week while using the topical ointment or powder.
2 Stars
Wound Healing
Take a standardized herbal extract providing 60 mg total triterpenoids once or twice per day
Applying an ointment containing gotu kola may speed healing of skin wounds.

One preliminary trial found that a extract helped heal infected wounds (unless they had reached bone). A review of French studies suggests that topical gotu kola can help wounds. One study found gotu kola extract helpful for preventing and treating enlarged scars (keloids). Standardized extracts of gotu kola containing up to 100% total triterpenoids are generally taken, providing 60 mg once or twice per day. Animal studies have shown that constituents in gotu kola, called asiaticosides, increase antioxidant levels during wound healing and facilitate repair of connective tissues.
1 Star
Burns
Refer to label instructions
Gotu kola contains substances that inhibit scar tissue from forming, it has been used in the medicinal systems of central Asia for centuries to treat numerous skin diseases.

has been used in the medicinal systems of central Asia for centuries to treat numerous skin diseases. Saponins in gotu kola beneficially affect collagen (the material that makes up connective tissue) to inhibit its production in hyperactive scar tissue following burns or wounds.
1 Star
Scars
Refer to label instructions
The primary active constituents of gotu kola may prevent excessive scar formation by inhibiting the production of collagen (the material that makes up connective tissue) at the wound site.

The primary active constituents of gotu kola are saponins (also called triterpenoids), which include asiaticoside, madecassoside and madasiatic acid. These saponins may prevent excessive scar formation by inhibiting the production of collagen (the material that makes up connective tissue) at the wound site. These constituents are also associated with promoting wound healing. One preliminary trial in humans found that a gotu kola extract improved healing of infected wounds (unless the infection had reached bone). Additionally, a review of French studies suggests that topical gotu kola can improve healing of burns and wounds. Another trial found gotu kola extract helpful for preventing and treating enlarged scars (keloids).
1 Star
Varicose Veins
Refer to label instructions
Supplementing with gotu kola may be helpful for varicose veins.

Oral supplementation with butcher's broom or may also be helpful for varicose veins.

Traditional Use (May Not Be Supported by Scientific Studies)

Gotu kola has been important in the medicinal systems of central Asia for centuries. In Sri Lanka, it was purported to prolong life, as the leaves are commonly eaten by elephants. Numerous skin diseases, ranging from poorly healing wounds to leprosy, have been treated with gotu kola. Gotu kola also has a historical reputation for boosting mental activity and for helping a variety of illnesses, such as high blood pressure, rheumatism, fever, and nervous disorders. Some of its common applications in Ayurvedic medicine include heart disease, water retention, hoarseness, bronchitis, and coughs in children, and as a poultice for many skin conditions.1

How It Works

Botanical names:
Centella asiatica

How It Works

The primary active constituents of gotu kola are saponins (also called triterpenoids), which include asiaticoside, madecassoside and madasiatic acid.2 These saponins may prevent excessive scar formation by inhibiting the production of collagen (the material that makes up connective tissue) at the wound site. These constituents are also associated with promoting wound healing. One preliminary trial in humans found that a gotu kola extract improved healing of infected wounds (unless the infection had reached bone).3 Additionally, a review of French studies suggests that topical gotu kola can improve healing of burns and wounds.4 Clinical trials have also shown it can help those with chronic venous insufficiency5, 6 Another trial found gotu kola extract helpful for preventing and treating enlarged scars (keloids).7

How to Use It

Dried gotu kola leaf can be made into a tea by adding 1–2 teaspoons (5–10 grams) to about 2/3 cup (150 ml) of boiling water and allowing it to steep for ten to fifteen minutes. Three cups (750 ml) are usually suggested per day. Fluid extract (1/2–1 teaspoon (3–5 ml) per day) or a tincture (2–4 teaspoons (10–20 ml) per day) are sometimes recommended. Standardized extracts containing up to 100% total saponins (triterpenoids), 60 mg once or twice per day, are frequently used in modern herbal medicine.8

Interactions

Botanical names:
Centella asiatica

Interactions with Supplements, Foods, & Other Compounds

At the time of writing, there were no well-known supplement or food interactions with this supplement.

Interactions with Medicines

As of the last update, we found no reported interactions between this supplement and medicines. It is possible that unknown interactions exist. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers' package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.

Side Effects

Botanical names:
Centella asiatica

Side Effects

Except for the rare person who is allergic to gotu kola, no significant adverse effects are experienced with internal or topical use of this herb.9

References

1. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 110-1.

2. Kartnig T. Clinical applications of Centella asiatica (L) Urb. In Herbs, Spices, and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology, vol. 3., Craker LE, Simon JE (eds). Phoenix, AZ: Oryx Press, 1986, 145-73.

3. Morisset R, Cote NG, Panisset JC, et al. Evaluation of the healing activity of hydrocotyle tincture in the treatment of wounds. Phytother Res 1987;1:117-21.

4. Kartnig T. Clinical applications of Centella asiatica (L) Urb. In Herbs, Spices, and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology, vol. 3., Craker LE, Simon JE (eds). Phoenix, AZ: Oryx Press, 1986, 145-73.

5. Brinkhaus B, Linder M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.

6. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiology 1986;37:420-1.

7. Bossé JP, Papillon J, Frenette G, et al. Clinical study of a new antikeloid drug. Ann Plastic Surg 1979;3:13-21.

8. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 173-83.

9. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 173-83.

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