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Home > Living Well > Health Library > Ornithine Alpha-Ketoglutarate
The amino acids ornithine and glutamine are combined to form ornithine
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Preliminary and controlled studies of people with severe burns and other types of injuries showed that supplementation with 10–30 grams of ornithine alpha-ketoglutarate (OKG) per day significantly improved wound healing and decreased the length of hospital stays. Improved healing from major trauma and surgery has also been demonstrated with oral supplements including several grams per day of glutamine.
Ornithine alpha-ketoglutarate (OKG) is formed from the amino acids ornithine and glutamine and is believed to facilitate muscle growth by enhancing the body's release of anabolic hormones. While this effect has been found in studies on hospitalized patients and elderly people, no studies on muscle growth in athletes using OKG have been published.
Optimal levels remain unknown, though 10 grams per day has been used in clinical trials.
Although the amino acids that comprise OKG are present in protein foods such as meat and poultry and fish, the OKG compound is found only in supplements.
A deficiency of OKG has not been reported.
Last Review: 03-24-2015
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