Cardiac Cachexia

Overview

Cardiac cachexia is unintentional severe weight loss caused by severe heart failure. The weight loss might be life-threatening.

Even with a very good appetite and high calorie intake, some people lose muscle mass.

Cardiac cachexia can require supplemental nutrition.

How it happens

  • Heart failure may cause blood to back up into the liver and intestines, and they may swell. This swelling can lead to nausea and decreased appetite.
  • Swelling of the intestines may not allow for adequate absorption of nutrients from the food you eat.
  • Heart failure may force you to work harder to breathe and cause your body temperature to increase. Both of these conditions burn calories.
  • In people with severe heart failure, tumor necrosis factor (TNF) and other signaling molecules in the bloodstream called cytokines can increase the metabolic rate of the tissues, thus burning more calories.

Related Information

Credits

Current as of: January 10, 2022

Author: Healthwise Staff
Medical Review:
Rakesh K. Pai MD, FACC - Cardiology, Electrophysiology
Martin J. Gabica MD - Family Medicine
Adam Husney MD - Family Medicine
Stephen Fort MD, MRCP, FRCPC - Interventional Cardiology

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